Gopal J Babu Selected Research

sarcolipin

1/2021	Sarcolipin haploinsufficiency prevents dystrophic cardiomyopathy in mdx mice.
10/2019	Sarcolipin overexpression impairs myogenic differentiation in Duchenne muscular dystrophy.
10/2017	Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice.
1/2014	Increased sarcolipin expression and adrenergic drive in humans with preserved left ventricular ejection fraction and chronic isolated mitral regurgitation.
12/2013	Increased sarcolipin expression and decreased sarco(endo)plasmic reticulum Ca2+ uptake in skeletal muscles of mouse models of Duchenne muscular dystrophy.
6/2012	Ablation of sarcolipin results in atrial remodeling.
6/2011	Decreased sarcolipin protein expression and enhanced sarco(endo)plasmic reticulum Ca2+ uptake in human atrial fibrillation.
2/2011	Ablation of phospholamban and sarcolipin results in cardiac hypertrophy and decreased cardiac contractility.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Gopal J Babu Research Topics

Disease

6	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2021 - 12/2013
5	Heart Failure 02/2017 - 05/2007
3	Fibrosis (Cirrhosis) 01/2021 - 06/2012
2	Cardiomyopathies (Cardiomyopathy) 01/2021 - 10/2017
2	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2020 - 05/2007
2	Cardiomegaly (Heart Hypertrophy) 02/2017 - 02/2011
2	Mitral Valve Insufficiency (Mitral Regurgitation) 01/2014 - 11/2013
2	Hypertrophy 03/2009 - 05/2007
1	Insulin Resistance 01/2022
1	Wasting Syndrome (Wasting Disease) 01/2021
1	Disease Progression 01/2021
1	Muscular Dystrophies (Muscular Dystrophy) 10/2019
1	Cardiovascular Diseases (Cardiovascular Disease) 02/2017
1	Acute-Phase Reaction 01/2014
1	Myasthenia Gravis 01/2014
1	Fistula 11/2013
1	Atrial Remodeling 06/2012
1	Atrial Fibrillation 06/2011
1	Urinary Bladder Neck Obstruction (Bladder Neck Obstruction) 03/2009
1	Myocardial Infarction 10/2007
1	Myocardial Ischemia (Ischemic Heart Diseases) 08/2007
1	Ventricular Remodeling 05/2007

Drug/Important Bio-Agent (IBA)

8	sarcolipinIBA 01/2021 - 02/2011
4	Adenosine Triphosphatases (ATPase)IBA 01/2021 - 02/2011
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 08/2007
3	Protein Isoforms (Isoforms)IBA 03/2009 - 05/2007
2	DystrophinIBA 01/2021 - 01/2020
2	Calcium-Transporting ATPases (Ca2+ ATPase)IBA 10/2017 - 05/2007
2	Messenger RNA (mRNA)IBA 06/2011 - 05/2007
2	phospholambanIBA 02/2011 - 05/2007
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	Insulin (Novolin)FDA Link 01/2022
1	CalciumIBA 01/2021
1	ras ProteinsIBA 02/2017
1	Cholinergic ReceptorsIBA 01/2014
1	erucylphosphocholineIBA 01/2014
1	AcetylcholinesteraseIBA 01/2014
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2014
1	muskIBA 01/2014
1	Adrenergic Agents (Adrenergic Drugs)IBA 01/2014
1	GTP-Binding Proteins (G-Protein)IBA 01/2014
1	Xanthine OxidaseIBA 11/2013
1	CollagenIBA 06/2012
1	Extracellular Matrix ProteinsIBA 06/2012
1	Myosin Heavy Chains (Myosin Heavy Chain)IBA 03/2009
1	Biological ProductsIBA 05/2007
1	Ventricular MyosinsIBA 05/2007
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 05/2007
1	Atrial Natriuretic Factor (ANF)IBA 05/2007

Therapy/Procedure

3	Therapeutics 01/2021 - 01/2014
1	Drug Therapy (Chemotherapy) 05/2007
1	Cardiac Resynchronization Therapy 05/2007